IFNG Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA, FN, WB |
Recommended Dilution | ELISA. Functional Assays: 10-50 µg/ml. Western Blot: This antibody detects a band of approximately 18 kDa. |
Reactivities | Chicken |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant Chicken Interferon Gamma |
Specificity | This antibody recognizes Chicken Interferon gamma (chIFN-gamma). This antibody can be used to neutralize chIFN-gamma activity and to discriminate the antiviral activity of chIFNg-amma from that of chIFN-alpha and chIFN-beta. |
Formulation | PBS State: Azide Free State: Liquid purified IgG fraction Stabilizer: None Preservative: None |
Concentration | 0.5 mg/ml |
Purification | Affinity Chromatography on protein G |
Gene Name | interferon, gamma |
Database Link | |
Background | Original studies investigating the properties of chicken Interferon (chIFN), revealed properties similar to mammalian IFN type I (IFNI), and it has since become apparent that there are at least three distinct chicken interferon proteins, designated as chIFN-alpha, chIFN-beta and chIFN-gamma. chIFN-gamma was first identified, when supernatant from chicken spleen cells stimulated with concanavalin A (ConA ), displayed macrophage-activating factor (MAF) activity - the principle function of mammalian type II IFNgamma. Several independent studies have since supported the existence of this chicken homolog, by the cloning of IFN-gamma cDNA from activated chicken T cells and demonstrating that recombinant chicken IFNgamma strongly upregulates the expression of MHC class II and iNOS genes. |
Synonyms | IFN-gamma, gamma IFN |
Reference Data |
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