S Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Recommended Dilution | ELISA: 1 ug/mL |
Reactivities | Virus |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | SARS Spike antibody was raised against a synthetic peptide corresponding to amino acids at the carboxy terminus of the SARS Spike glycoprotein. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | SARS Spike Antibody is affinity chromatography purified via peptide column. |
Background | SARS Spike Antibody: A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2. |
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