Dysbindin (DTNBP1) Rabbit Polyclonal Antibody

CAT#: TA300078

Rabbit Polyclonal Antibody against DTNBP1

Product Images

Western blot analysis of Dtnbp1 (arrow) using rabbit polyclonal Dysbindin (Dtnbp1) Antibody (C-term) (Cat.#TA300078).

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  Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with Dtnbp1 Antibody (C-term) (Cat.#TA300078), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:10~50
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: This Dtnbp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of human Dtnbp1.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: dystrobrevin binding protein 1
• Database Link:
  NP_115498
  Entrez Gene 94245 MouseEntrez Gene 84062 Human
  UniProt ID Q96EV8
• Background: Dtnp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this protein are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.
• Synonyms: BLOC1S8; DBND; HPS7; My031; SDY

Reference Data

• Protein Families: Druggable Genome