XRCC3 Rabbit Polyclonal Antibody

CAT#: TA301486

Rabbit Polyclonal Antibody against XRCC3

Product Images

Western Blot: XRCC3 Antibody TA301486 - Detection of XRCC3 (38 kDa) from HeLa cell extract using TA301486 (1:2500). Lanes 1 and 2 contain HTC116 and Hela whole cell extracts, respectively.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Immunoprecipitation, Western Blot: 1:5000, ICC/IF (Negative)
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic partial peptide of human XRCC3.
• Formulation: PBS and 0.05% sodium azide
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 3
• Database Link:
  NP_005423
  Entrez Gene 7517 Human
  UniProt ID O43542
• Background: Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homolgs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes. XRCC3 (x-ray cross complementing) was first identified as a human gene complementing the DNA damage sensitivity, chromosonal instability and impaired growth of the mutant hamster cell line irs1SF. This fact coupled with XRCC3 being a member of the RAD51 gene family have implied a role in the repair of DNA damage by homologous recombination.
• Synonyms: CMM6

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Homologous recombination