TRAP alpha (SSR1) Rabbit Polyclonal Antibody

CAT#: TA302066

Rabbit Polyclonal Antibody against SSR1 (N-term)

Product Images

Western blot analysis of SSR1 (arrow) using rabbit SSR1 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SSR1 gene (Lane 2) (Origene Technologies).

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  SSR1 Antibody (N-term) (Cat. #TA302066) western blot analysis in Hela, mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the SSR1 antibody detected the SSR1 protein (arrow).

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  Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with SSR1 antibody (N-term) (Cat.#TA302066), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC: 1:10~50, WB: 1:1000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This SSR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human SSR1.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32235 Da
• Gene Name: signal sequence receptor subunit 1
• Database Link:
  NP_003135
  Entrez Gene 107513 MouseEntrez Gene 6745 Human
  UniProt ID P43307
• Background: The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.
• Synonyms: TRAPA

Reference Data

• Protein Families: Druggable Genome, Transmembrane