AK3L1 (AK4) Rabbit Polyclonal Antibody

CAT#: TA302218

Rabbit Polyclonal Antibody against AK3L1 (C-term H38)

Product Images

The anti-AK3 Pab (Cat. #TA302218) is used in Western blot to detect AK3 in mouse kidney tissue lysate.

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  Western blot analysis of AK3 (arrow) using rabbit polyclonal AK3 Antibody (C-term H38) (Cat. #TA302218). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AK3 gene (Lane 2) (Origene Technologies).

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  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:50~100
• Reactivities: Human, Mouse (Predicted: Rat)
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This AK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the C-terminal region of human AK3.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25268 Da
• Gene Name: adenylate kinase 4
• Database Link:
  NP_037542
  Entrez Gene 11639 MouseEntrez Gene 29223 RatEntrez Gene 205 Human
  UniProt ID P27144
• Background: AK3 is a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated.
• Synonyms: AK3; AK3L1; AK3L2; AK 4

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism