CNOT4 Rabbit Polyclonal Antibody

CAT#: TA302282

Rabbit Polyclonal Antibody against CNOT4 (N-term)

Product Images

Western blot analysis of CNOT4 (arrow) using rabbit polyclonal CNOT4 Antibody (N-term) ([RB11916]). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CNOT4 gene (Lane 2) (Origene Technologies).

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  CNOT4 Antibody (N-term) (Cat. #TA302282) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CNOT4 antibody detected the CNOT4 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This CNOT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-84 amino acids from the N-terminal region of human CNOT4.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 63510 Da
• Gene Name: CCR4-NOT transcription complex subunit 4
• Database Link:
  NP_001008226
  Entrez Gene 53621 MouseEntrez Gene 4850 Human
  UniProt ID O95628
• Background: CNOT4 has intrinsic E3 ubiquitin ligase activity. Binding of the CNOT4 RING finger to the ubiquitin-conjugating enzyme (E2) UbcH5B is highly selective. The CCR4-NOT complex functions as a global regulator of RNA polymerase II transcription.
• Synonyms: CLONE243; NOT4; NOT4H

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: RNA degradation