FLAP (ALOX5AP) Goat Polyclonal Antibody
Other products for "ALOX5AP"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1:128,000. WB: 0.1-0.3µg/ml. |
Reactivities | Human |
Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Peptide with sequence C-HKVEHESRTQNGR, from the internal region of the protein sequence according to NP_001620.2. |
Formulation | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
Concentration | lot specific |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 21780 Da |
Gene Name | arachidonate 5-lipoxygenase activating protein |
Database Link | |
Background | This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. [provided by RefSeq] |
Synonyms | FLAP |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Documents
Product Manuals |
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