IL18BP Rabbit Monoclonal Antibody [Clone ID: EP1088Y]

CAT#: TA303770

Rabbit monoclonal antibody against IL-18BP (EP1088Y )

Product Images

Western blot - IL18 binding protein antibody [EP1088Y]; Anti-IL18 binding protein antibody [EP1088Y] at 1/500 dilution + HeLa cell lysate at 10 ug.Secondary.Goat anti rabbit IgG HRP antibody at 1/2000 dilution.Predicted band size : 22 kDa.Observed band size : 44 kDa.

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  Immunohistochemistry (Paraffin-embedded sections) - IL18 binding protein antibody [EP1088Y]; Ab52914 at 1/50 dilution staining human tonsil tissue; paraffin embedded.

Specifications

Product Data

• Clone Name: EP1088Y
• Applications: IHC, WB
• Recommended Dilution: WB: 1:2000 - 1:5000; FC: 1:10; IHC-P: Use at an assay dependent dilution
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues near the N-terminus of human IL18BP was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 18 binding protein
• Database Link:
  NP_001034748
  Entrez Gene 16068 MouseEntrez Gene 84388 RatEntrez Gene 10068 Human
  UniProt ID O95998
• Background: The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
• Synonyms: IL18BPa
• Note: Is unsuitable for ICC/IF or IP.

Reference Data

• Protein Families: Druggable Genome, Secreted Protein