FLAP (ALOX5AP) Goat Polyclonal Antibody

CAT#: TA305631

Goat Anti-FLAP / ALOX5AP (C Term) Antibody

Specifications

Product Data

• Recommended Dilution: WB: 1-3ug/ml.
• Reactivities: Human
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-KTISTTISPLLLIP, from the C Terminus of the protein sequence according to NP_001620.2.
• Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: arachidonate 5-lipoxygenase activating protein
• Database Link:
  NP_001620
  Entrez Gene 241 Human
  UniProt ID P20292
• Background: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. [provided by RefSeq]
• Synonyms: FLAP

Reference Data

• Protein Families: Druggable Genome, Transmembrane