SH2D1B Goat Polyclonal Antibody

CAT#: TA305804

Goat Anti-EAT2 phospho (Y127) Antibody (Phospho-Specific)

Specifications

Product Data

• Recommended Dilution: WB: 0.3-1ug/ml.
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Phosphorylated peptide with sequence C-NSNSDpYVDVLP, from the internal region of the protein sequence according to NP_444512.2
• Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SH2 domain containing 1B
• Database Link:
  NP_444512
  Entrez Gene 117157 Human
  UniProt ID O14796
• Background: By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]). [supplied by OMIM]
• Synonyms: EAT2

Reference Data

• Protein Pathways: Natural killer cell mediated cytotoxicity