CTRP3 (C1QTNF3) Rabbit Polyclonal Antibody

CAT#: TA306233

Rabbit Polyclonal CTRP3 Antibody

Product Images

Western blot analysis of CTRP3 in mouse heart cell lysate with CTRP3 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.

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  Immunohistochemistry of CTRP3 in mouse heart tissue with CTRP3 antibody at 2 ug/ml.

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  Immunofluorescence of CTRP3 in Mouse Heart tissue with CTRP3 antibody at 10 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2 ug/mL, IF: 10 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CTRP3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human CTRP3. The immunogen is located within amino acids 90 - 140 of CTRP3.
• Formulation: PBS containing 0.02% sodium azide.
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: C1q and tumor necrosis factor related protein 3
• Database Link:
  NP_112207
  Entrez Gene 81799 MouseEntrez Gene 114899 Human
  UniProt ID Q9BXJ4
• Background: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-?-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development (5).
• Synonyms: C1ATNF3; CORCS; CORS; CORS-26; CORS26; CTRP3

Reference Data

• Protein Families: Secreted Protein