GRTP1 Rabbit Polyclonal Antibody

CAT#: TA306569

Rabbit Polyclonal GRTP1 Antibody

Product Images

Western blot analysis of GRTP1 in SK-N-SH cell lysate with GRTP1 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: GRTP1 antibody was raised against a 16 amino acid peptide from near the center of human GRTP1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: growth hormone regulated TBC protein 1
• Database Link:
  NP_078995
  Entrez Gene 66790 MouseEntrez Gene 361180 RatEntrez Gene 79774 Human
  UniProt ID Q5TC63
• Background: Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver (1). GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment. At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.
• Synonyms: TBC1D6