Matrilin 2 (MATN2) Rabbit Polyclonal Antibody

CAT#: TA306751

Rabbit Polyclonal MATN2 Antibody

Product Images

Western blot analysis of MATN2 in human liver tissue lysate with MATN2 antibody at (A) 1 and (B) 2 ug/ml.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MATN2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human MATN2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: matrilin 2
• Database Link:
  NP_002371
  Entrez Gene 17181 MouseEntrez Gene 299996 RatEntrez Gene 4147 Human
  UniProt ID O00339
• Background: Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration.
• Synonyms: matrilin 2; PRO219

Reference Data

• Protein Families: Secreted Protein