SCARA5 Rabbit Polyclonal Antibody

CAT#: TA306806

Rabbit Polyclonal SCARA5 Antibody

Product Images

Western blot analysis of SCARA5 in human liver tissue lysate with SCARA5 antibody at 1 ug/mL.

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  Immunocytochemistry of SCARA5 in HepG2 cells with SCARA5 antibody at 2.5 ug/mL.

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  Immunofluorescence of SCARA5 in HepG2 cells with SCARA5 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SCARA5 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SCARA5.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: scavenger receptor class A member 5
• Database Link:
  NP_776194
  Entrez Gene 71145 MouseEntrez Gene 286133 Human
  UniProt ID Q6ZMJ2
• Background: Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARA5 is a cell-surface receptor that contains that collagen-like domain and N-terminal scavenger receptor cysteine rich domain typical of the class A scavenger receptor subfamily. Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low density lipoprotein. Instead, SCARA5 binds serum ferritin and mediates its endocytosis from the cell surface, indicating SCARA5 may play a role in non-transferrin iron delivery. At least four isoforms of SCARB1 are known to exist.
• Synonyms: NET33; Tesr

Reference Data

• Protein Families: Druggable Genome, Transmembrane