hHR23A (RAD23A) Rabbit Monoclonal Antibody [Clone ID: EPR4818]

CAT#: TA307254

Rabbit monoclonal antibody against RAD23A(clone EPR4818)

Product Images

Western blot - hHR23A antibody [EPR4818]; All lanes : Anti-hHR23A antibody [EPR4818] at 1/10000 dilution.Lane 1 : MCF7 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Raji cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 40 kDa.

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  Flow Cytometry - hHR23A antibody [EPR4818]; TA307254 at 1/10 dilution staining hHR23A in permeabilized Jurkat cells by Flow cytometry (shown in red). Rabbit IgG (negative) in green.

Specifications

Product Data

• Clone Name: EPR4818
• Applications: FC, WB
• Recommended Dilution: WB: 1:10000 - 1:50000; FC: 1:10 - 1:100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues in human RAD23A was used as an immunogen.
• Formulation: pH: 7.40
  Preservative: 0.01% Sodium azide
  Constituents: 50% Glycerol, 0.05% BSA
• Purification: Tissue culture supernatant
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: RAD23 homolog A, nucleotide excision repair protein
• Database Link:
  NP_005044
  Entrez Gene 19358 MouseEntrez Gene 361381 RatEntrez Gene 5886 Human
  UniProt ID P54725
• Background: RAD23A is one of two human homologs of Saccharomyces cerevisiae RAD23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. RAD23A contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
• Synonyms: HHR23A; HR23A
• Note: Is unsuitable for ICC,IHC-P or IP.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Nucleotide excision repair