SEPTIN7 Rabbit Polyclonal Antibody

CAT#: TA307975

Rabbit Polyclonal antibody to SEPT7 (septin 7)

Product Images

Sample (30 ug of whole cell lysate). A: MOLT4. 7.5% SDS PAGE. TA307975 diluted at 1:500

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 278 of SEPT7 (Uniprot ID#Q16181)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51 kDa
• Gene Name: septin 7
• Database Link:
  NP_001011553
  Entrez Gene 64551 RatEntrez Gene 235072 MouseEntrez Gene 989 Human
  UniProt ID Q16181
• Background: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. Although the exact function of this gene has not yet been determined, its high similarity to yeast CDC10 and the high conservative nature of eukaryotic cell cycle machinery suggest a similar role to that of its yeast counterpart. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
• Synonyms: CDC3; CDC10; NBLA02942; SEPT7A
• Note: Seq homology of immunogen across species: Mouse (98%), Rat (99%)