TNFRSF19L (RELT) Rabbit Polyclonal Antibody

CAT#: TA308068

Rabbit Polyclonal antibody to RELT (RELT tumor necrosis factor receptor)

Product Images

Sample (30 ug whole cell lysate). A:HeLa S3. 10% SDS PAGE. TA308068 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded U87 xenograft, using RELT (TA308068) antibody at 1:100 dilution.

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  Immunofluorescence analysis of methanol-fixed A431, using RELT (TA308068) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 35 and 396 of RELT (Uniprot ID#Q969Z4)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: RELT tumor necrosis factor receptor
• Database Link:
  NP_116260
  Entrez Gene 320100 MouseEntrez Gene 361615 RatEntrez Gene 84957 Human
  UniProt ID Q969Z4
• Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq]
• Synonyms: TNFRSF19L; TRLT
• Note: Seq homology of immunogen across species: Mouse (87%), Rat (86%)

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction