Arginase 1 (ARG1) Rabbit Polyclonal Antibody

CAT#: TA308162

Rabbit Polyclonal antibody to Arginase I (arginase, liver)

Product Images

Sample (20 ug of whole cell lysate). A: mouse liver. 10% SDS PAGE. TA308162 diluted at 1:50000.

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  Arginase 1 antibody detects ARG1 protein by Western blot analysis. A. 30 ug HepG2 whole cell lysate/extract. 10 % SDS-PAGE. Arginase 1 antibody (TA308162) dilution: 1:1000

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  Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using arginase I (TA308162) antibody at 1:500 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using arginase I (TA308162) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:50000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 322 of Arginase I (Uniprot ID#P05089)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35 kDa
• Gene Name: arginase 1
• Database Link:
  NP_000036
  Entrez Gene 11846 MouseEntrez Gene 383 Human
  UniProt ID P05089
• Background: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq]
• Synonyms: arginase; arginase 1; liver; liver-type arginase; OTTHUMP00000017209; type I arginase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Metabolic pathways