EIF2B2 Rabbit Polyclonal Antibody

CAT#: TA308277

Rabbit polyclonal antibody to eIF2B beta (eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa)

Product Images

Sample (30 ug of whole cell lysate). A: A431. 10% SDS PAGE. TA308277 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded Colon ca, using EIF2B beta (TA308277) antibody at 1:250 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 88 and 323 of EIF2B beta (Uniprot ID#P49770)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 39 kDa
• Gene Name: eukaryotic translation initiation factor 2B subunit beta
• Database Link:
  NP_055054
  Entrez Gene 84005 RatEntrez Gene 217715 MouseEntrez Gene 8892 Human
  UniProt ID P49770
• Background: Eukaryotic initiation factor-2B (EIF2B) is a GTP exchange protein essential for protein synthesis. It consists of alpha (EIF2B1; MIM 606686), beta (EIF2B2), gamma (EIF2B3; MIM 606273), delta (EIF2B4; MIM 606687), and epsilon (EIF2B5; MIM 603945) subunits. EIF2B activates its EIF2 (see MIM 603907) substrate by exchanging EIF2-bound GDP for GTP. [supplied by OMIM]
• Synonyms: EIF-2Bbeta; EIF2B
• Note: Seq homology of immunogen across species: Mouse (96%), Chicken (90%), Rabbit (98%), Rat (94%), Zebrafish (85%), Bovine (98%), Xenopus tropicalis (87%)