PARP3 Rabbit Polyclonal Antibody

CAT#: TA308450

Rabbit Polyclonal antibody to PARP3 (poly (ADP-ribose) polymerase family, member 3)

Product Images

PARP3 antibody detects PARP3 protein by Western blot analysis. A. 30 ug A431 whole cell lysate/extract. B. 30 ug HeLa whole cell lysate/extract. C. 30 ug A375 whole cell lysate/extract. 7.5 % SDS-PAGE. PARP3 antibody (TA308450) dilution: 1:1000

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  Sample (50 ug of whole cell lysate). A: mouse heart. 7.5% SDS PAGE. TA308450 diluted at 1:1000.

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  PARP3 antibody detects PARP3 protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. 7.5 % SDS-PAGE. PARP3 antibody (TA308450) dilution: 1:1000

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  Immunohistochemical analysis of paraffin-embedded OVCA, using PARP3 (TA308450) antibody at 1:100 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PARP3 (TA308450) antibody at 1:500 dilution.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 63 and 370 of PARP3 (Uniprot ID#Q9Y6F1)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 60 kDa
• Gene Name: poly(ADP-ribose) polymerase family member 3
• Database Link:
  NP_001003931
  Entrez Gene 235587 MouseEntrez Gene 10039 Human
  UniProt ID Q9Y6F1
• Background: The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
• Synonyms: ADPRT3; ADPRTL2; ADPRTL3; ARTD3; IRT1; PADPRT-3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair