UBE2B Rabbit Polyclonal Antibody
CAT#: TA308525
Rabbit Polyclonal antibody to UBE2B (ubiquitin-conjugating enzyme E2B (RAD6 homolog))
Other products for "UBE2B"
Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | ICC/IF:1:100-1:1000; WB:1:500-1:10000 |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 152 of UBE2B |
Formulation | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 17 kDa |
Gene Name | ubiquitin conjugating enzyme E2 B |
Database Link | |
Background | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq] |
Synonyms | E2-17kDa; HHR6B; HR6B; RAD6B; UBC2 |
Note | Seq homology of immunogen across species: Rat (100%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%) |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Ubiquitin mediated proteolysis |
Documents
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