ARAP1 Rabbit Polyclonal Antibody

CAT#: TA308584

Rabbit polyclonal antibody to ARAP1 (centaurin, delta 2)

Product Images

Sample (30 ug of whole cell lysate). A: H1299. 5% SDS PAGE. TA308584 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1388 and 1450 of ARAP1 (Uniprot ID#Q96P48)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 162 kDa
• Gene Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
• Database Link:
  NP_001035207
  Entrez Gene 116985 Human
  UniProt ID Q96P48
• Background: The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: CENTD2

Reference Data

• Protein Pathways: Endocytosis