MUC2 Rabbit Polyclonal Antibody

CAT#: TA308821

Rabbit Polyclonal antibody to MUC2 (mucin 2, oligomeric mucus/gel-forming)

Product Images

Sample (30ug whole cell lysate). A:Raji. 5% SDS PAGE. TA308821 diluted at 1:3000

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  Immunohistochemical analysis of paraffin-embedded SAS xenograft, using MUC2 (TA308821) antibody at 1:500 dilution.

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  MUC2 antibody [C3], C-term detects MUC2 protein at secreted on mouse intestine by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. MUC2 antibody [C3], C-term (TA308821) dilution: 1:500.

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  MUC2 antibody [C3], C-term detects MUC2 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: MUC2 protein stained by MUC2 antibody [C3], C-term (TA308821) diluted at 1:500. Blue: Hoechst 3334

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 4362 and 4456 of MUC2 (Uniprot ID#Q02817)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 540 kDa
• Gene Name: mucin 2, oligomeric mucus/gel-forming
• Database Link:
  NP_002448
  Entrez Gene 4583 Human
• Background: This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq]
• Synonyms: MLP; MUC-2; SMUC
• Note: Seq homology of immunogen across species: Bovine (86%)

Reference Data

• Protein Pathways: Vibrio cholerae infection