IFNAR1 Rabbit Polyclonal Antibody

CAT#: TA308908

Rabbit Polyclonal antibody to interferon alpha Receptor 1 (interferon (alpha, beta and omega) receptor 1)

Product Images

interferon alpha Receptor 1 antibody [N1N3] detects interferon alpha Receptor 1 protein by western blot analysis. A.50 ug mouse brain lysate/extract. 7.5 % SDS-PAGE. interferon alpha Receptor 1 antibody [N1N3] (TA308908) dilution: 1:1000

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  Sample (30 ug of whole cell lysate). A: A431. 7.5% SDS PAGE. TA308908 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 3 and 240 of interferon alpha Receptor 1 (Uniprot ID#P17181)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 64 kDa
• Gene Name: interferon alpha and beta receptor subunit 1
• Database Link:
  NP_000620
  Entrez Gene 3454 Human
  UniProt ID P17181
• Background: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. [provided by RefSeq]
• Synonyms: AVP; IFN-alpha-REC; IFNAR; IFNBR; IFRC

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Toll-like receptor signaling pathway