AP1S2 Rabbit Polyclonal Antibody

CAT#: TA308977

Rabbit polyclonal antibody to AP1S2 (adaptor-related protein complex 1, sigma 2 subunit)

Product Images

Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. TA308977 diluted at 1:1000.

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  Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using AP1S2 (TA308977) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 157 of AP1S2 (Uniprot ID#P56377)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 19 kDa
• Gene Name: adaptor related protein complex 1 sigma 2 subunit
• Database Link:
  NP_003907
  Entrez Gene 302671 RatEntrez Gene 8905 Human
  UniProt ID P56377
• Background: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq]
• Synonyms: DC22; MRX59; MRXS5; MRXS21; MRXSF; PGS; SIGMA1B
• Note: Seq homology of immunogen across species: Rat (100%), Chimpanzee (100%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysosome