TAOK2 Rabbit Polyclonal Antibody

CAT#: TA309251

Rabbit Anti-TAO2 (Ser181) Antibody (Phospho-Specific)

Product Images

Western blot of rat cortex lysate showing specific immunolabeling of the ~120k TAO2 phosphorylated at Ser181 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: λ-Ptase). The blot is identical to the control except that it was incubated in λ-Ptase (1200 units for 30 min) before being exposed to the Ser181 TAO2 antibody. The immunolabeling is completely eliminated by treatment with λ-Ptase.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser181 conjugated to KLH
• Formulation: 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 120 kDa
• Gene Name: TAO kinase 2
• Database Link:
  NP_057235
  Entrez Gene 64666 RatEntrez Gene 381921 MouseEntrez Gene 9344 Human
  UniProt ID Q9UL54
• Background: TAOK2 is a serine/threonine kinase that has a role in cell signaling, microtubule organization and stability, and in apoptosis (Moore et al., 2000 [PubMed 10660600]; Zihni et al., 2007 [PubMed 17158878]). [supplied by OMIM]
• Synonyms: MAP3K17; PSK; PSK1; PSK1-BETA; TAO1; TAO2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: MAPK signaling pathway