Transglutaminase 2 (TGM2) Goat Polyclonal Antibody
Other products for "TGM2"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1-3ug/ml |
Reactivities | Mouse, Rat |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Peptide with sequence C-ERDLYLENPEIKIR, from the internal region of the protein sequence according to NP_004604.2. |
Formulation | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | transglutaminase 2 |
Database Link | |
Background | Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Synonyms | G-ALPHA-h; GNAH; HEL-S-45; TG2; TGC |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Huntington's disease |
Documents
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