GAB1 Rabbit Polyclonal Antibody

CAT#: TA311944

Rabbit polyclonal Gab1 (Tyr627) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from HuvEc cells treated with EGF (200ng/ml, 10mins), using Gab1 (phospho-Tyr627) antibody.The lane on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:3000, ELISA: 1:10000
• Reactivities: Human, Mouse
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Gab1 around the phosphorylation site of tyrosine 627 (V-E-YP-L-D)
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: GRB2 associated binding protein 1
• Database Link:
  NP_002030
  Entrez Gene 14388 MouseEntrez Gene 2549 Human
  UniProt ID Q13480
• Synonyms: GRB2-associated binding protein 1
• Note: Gab1(phospho-Tyr627) antibody detects endogenous levels of Gab1 only when phosphorylated at tyrosine 627.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: ErbB signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma