Chk2 (CHEK2) Rabbit Polyclonal Antibody

CAT#: TA312769

Rabbit polyclonal Chk2 (Thr68) antibody(Phospho-specific)

Product Images

Western blot analysis of the extracts from Jurkat cells untreated or treated with UV using Chk2 (Ab-68) Antibody and Chk2 (Phospho-Thr68) Antibody.The lane on the right is treated with the synthesized peptide.

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  Immunohistochemical analysis of paraffin- embedded lung carcinoma. Left: Using Chk2 (Phospho-Thr68) Antibody; Right: The same antibody preincubated with synthesized phosphopeptide.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:20000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Chk2 around the phosphorylation site of Threonine 68 (V-S-TP-Q-E).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: checkpoint kinase 2
• Database Link:
  NP_665861
  Entrez Gene 50883 MouseEntrez Gene 114212 RatEntrez Gene 11200 Human
  UniProt ID O96017
• Synonyms: CDS1; CHK2; hCds1; HuCds1; LFS2; PP1425; RAD53
• Note: Chk2 (Phospho-Thr68) Antibody detects endogenous levels of Chk2 only when phosphorylated at Threonine 68.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Stem cell - Pluripotency
• Protein Pathways: Cell cycle, p53 signaling pathway