RAF1 Rabbit Polyclonal Antibody

CAT#: TA313055

Rabbit polyclonal Raf1 (Tyr341) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from Jurkat cells, treated with Paclitaxel (1uM, 24hours), using Raf1 (Phospho-Tyr341) antibody.The lane on the right is treated with the synthesized peptide.

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  Immunohistochemistry analysis of paraffin-embedded human pancreas tissue using Raf1 (Phospho-Tyr341) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:1000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Raf1 around the phosphorylation site of tyrosine 341 (S-Y-YP-W-E).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Raf-1 proto-oncogene, serine/threonine kinase
• Database Link:
  NP_002871
  Entrez Gene 24703 RatEntrez Gene 110157 MouseEntrez Gene 5894 Human
  UniProt ID P04049
• Synonyms: c-Raf; CMD1NN; CRAF; NS5; Raf-1
• Note: Raf1 (Phospho-Tyr341) antibody detects endogenous levels of Raf1 only when phosphorylated at tyrosine 341.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Acute myeloid leukemia, B cell receptor signaling pathway, Bladder cancer, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway