BTK Rabbit Polyclonal Antibody

CAT#: TA313378

Rabbit polyclonal BTK (Tyr551) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from HeLa cells, treated with H2O2 (100uM, 30mins), using BTK (phospho-Tyr551) antibody.The lane on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:3000, ELISA: 1:40000
• Reactivities: Human: Tyr551, Mouse: Tyr551, Rat:Tyr552
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human BTK around the phosphorylation site of tyrosine 551 (D-E-YP-T-S).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Bruton tyrosine kinase
• Database Link:
  NP_000052
  Entrez Gene 12229 MouseEntrez Gene 367901 RatEntrez Gene 695 Human
  UniProt ID Q06187
• Synonyms: AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
• Note: BTK (phospho-Tyr551) antibody detects endogenous levels of BTK only when phosphorylated at tyrosine 551.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency