BRCA1 Rabbit Polyclonal Antibody

CAT#: TA313516

Rabbit polyclonal BRCA1 (Ser1457) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from 293 cells, treated with epo (20U/ml, 15mins), using BRCA1 (Phospho-Ser1457) antibody.The lane on the right is treated with the synthesized peptide.

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  Western blot analysis of extracts from 293 cells (Lane 2), using BRCA1 (Phospho-Ser1457) Antibody. The lane on the left is treated with synthesized peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:3000, ELISA: 1:1000
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human BRCA1 around the phosphorylation site of serine 1457 (L-T-SP-Q-K).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: BRCA1, DNA repair associated
• Database Link:
  NP_009225
  Entrez Gene 672 Human
  UniProt ID P38398
• Synonyms: BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53
• Note: BRCA1 (Phospho-Ser1457) antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 1457.

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Ubiquitin mediated proteolysis