TEM8 (ANTXR1) Rabbit Polyclonal Antibody

CAT#: TA318947

Rabbit polyclonal anti-TEM-8/ATR1 antibody

Product Images

Western blot analysis of TEM8 using lysates from rat kidney (Lane 1), mouse small intestine (Lane 2), and Jurkat cells (Lane 3).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 484 of Mouse TEM8
• Formulation: 100 µg (0.2mg/ml) affinity purified rabbit anti-TEM8/ATR1 polyclonal antibody in phosphate-buffered saline (PBS) containing 0.5% BSA, 30% glycerol, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: anthrax toxin receptor 1
• Database Link:
  NP_060623
  Entrez Gene 69538 MouseEntrez Gene 362393 RatEntrez Gene 84168 Human
  UniProt ID Q9H6X2
• Background: Tumor Endothelial Markers (TEMs, TEM 1-9) are recently identified genes, whose expression is elevated in tumor-associated endothelium. TEMs are barely detectable in normal endothelial cells. TEM8 has been shown to interact with C5 domain of collagen a3(VI), a protein also preferentially expressed in tumor endothelium. It is thought that TEM8 may play a role in tumor angiogenesis.
• Synonyms: ATR; GAPO; TEM8

Reference Data

• Protein Families: Druggable Genome, Transmembrane