hHR23A (RAD23A) Goat Polyclonal Antibody
Other products for "RAD23A"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1:4,000 - 1:16,000, WB: 1:500 - 1:2,000 |
Reactivities | Human |
Host | Goat |
Clonality | Polyclonal |
Immunogen | This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 122-135 of human HR23A protein. |
Formulation | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | RAD23 homolog A, nucleotide excision repair protein |
Database Link | |
Synonyms | HHR23A; HR23A |
Note | HR23A (also known as UV excision repair protein RAD23 homolog A) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Nucleotide excision repair |
Documents
Product Manuals |
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