DIAPH2 Rabbit Polyclonal Antibody
Other products for "DIAPH2"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1:12,000 - 1:60,000, WB: 1:1,000 - 1:6,000, IP: 1:100 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 1085-1101 of Human DIA-2. |
Formulation | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | diaphanous related formin 2 |
Database Link | |
Synonyms | DIA; DIA2; DRF2; POF; POF2 |
Note | DIA-2 (also called DIA drome, Dia2, DIAPH2, Diaphanous 2, Diaphanous related formin 2, Diaphorase 2, DRF2, POF and POF2) may play a role in the development and normal function of the ovaries. Mutations of this gene have been linked to premature ovarian failure. Alternative splicing results in two protein isoforms. Furthermore, each splice variant undergoes additional splicing in the 3' UTR. Overall 4 splice variants have been described. DIA-2 is expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes and can be found from E16 in ovary and testis and during P6-P16 during differentiation of ovarian follicles. Isoform 1 is referred to as DIA-156, whereas isoform 2 is called DIA-12C. |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Regulation of actin cytoskeleton |
Documents
Product Manuals |
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