beta TRCP2 (FBXW11) Rabbit Polyclonal Antibody
Other products for "FBXW11"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1:10,000 – 1:100,000, WB: 1:200 to 1:1,000, IF: User Optimized |
Reactivities | Bovine, Chicken, Human, Monkey, Mouse, Dog |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the N-terminal of human βTrCP2 protein. |
Formulation | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | F-box and WD repeat domain containing 11 |
Database Link | |
Synonyms | BTRC2; BTRCP2; FBW1B; Fbw11; FBXW1B; Hos |
Note | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Hedgehog signaling pathway, Oocyte meiosis, Ubiquitin mediated proteolysis, Wnt signaling pathway |
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