BOK Rabbit Polyclonal Antibody
Other products for "BOK"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 5 ug/mL |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK. |
Formulation | BOK Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | BOK Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | BCL2-related ovarian killer |
Database Link | |
Background | BOK Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation. |
Synonyms | BCL2L9; BOKL |
Reference Data | |
Protein Families | Druggable Genome |
Documents
Product Manuals |
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