BOK Rabbit Polyclonal Antibody

CAT#: TA319621

Rabbit Polyclonal BOK Antibody

Product Images

Immunohistochemistry of BOK in human brain tissue with BOK antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 5 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK.
• Formulation: BOK Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: BOK Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: BCL2-related ovarian killer
• Database Link:
  NP_115904
  Entrez Gene 666 Human
  UniProt ID Q9UMX3
• Background: BOK Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.
• Synonyms: BCL2L9; BOKL

Reference Data

• Protein Families: Druggable Genome