TCF12 Rabbit Polyclonal Antibody

CAT#: TA319714

Rabbit Polyclonal TCF12 Antibody

Product Images

Western blot analysis of TCF12 in HeLa cell lysate with TCF12 antibody at (A) 0.5 and (B) 1 ug/mL.

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  Immunocytochemistry of TCF12 in HeLa cells with TCF12 antibody at 10 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, ICC: 10 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TCF12 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TCF12.
• Formulation: TCF12 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TCF12 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: transcription factor 12
• Database Link:
  NP_003196
  Entrez Gene 21406 MouseEntrez Gene 25720 RatEntrez Gene 6938 Human
  UniProt ID Q99081
• Background: TCF12 Antibody: TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.
• Synonyms: bHLHb20; CRS3; HEB; HsT17266; HTF4

Reference Data

• Protein Families: Druggable Genome, Transcription Factors