USP10 Rabbit Polyclonal Antibody

CAT#: TA319768

Rabbit Polyclonal USP10 Antibody

Product Images

Western blot analysis of USP10 in Jurkat cell lysate with USP10 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunofluorescence of USP10 in Jurkat cells with USP10 antibody at 20 ug/mL.

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  Immunocytochemistry of USP10 in Jurkat cells with USP10 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 20 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: USP10 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human USP10.
• Formulation: USP10 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: USP10 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ubiquitin specific peptidase 10
• Database Link:
  NP_001259004
  Entrez Gene 22224 MouseEntrez Gene 9100 Human
  UniProt ID Q14694
• Background: USP10 Antibody: USP10, also known as ubiquitin specific peptidase 10, belongs to the ubiquitin-specific protease family of cysteine proteases. USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 has been identified as a subunit of DNA-bound androgen receptor (AR) complexes and may play a role in the activity of the DNA-bound androgen receptor complex. USP10 also acts as an essential regulator of p53/TP53 stability and is thought to function as a tumor suppressor.
• Synonyms: UBPO

Reference Data

• Protein Families: Druggable Genome, Protease