Bim (BCL2L11) Mouse Monoclonal Antibody [Clone ID: 1C2C8]

CAT#: TA319805

Mouse Bim Monoclonal Antibody

Product Images

Western blot analysis of (A) 5 and (B) 25 ng of Bim recombinant protein with Bim antibody at 1 ug/mL.

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  Immunofluorescence of Bim in K562 cells with Bim antibody at 20 ug/mL.

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  Immunocytochemistry of Bim in K562 cells with Bim antibody at 10 ug/mL.

Specifications

Product Data

• Clone Name: 1C2C8
• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.
• Formulation: Bim Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Bim Monoclonal Antibody is immunoaffinity chromotography purified IgG.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: BCL2 like 11
• Database Link:
  NP_001191035
  Entrez Gene 12125 MouseEntrez Gene 10018 Human
  UniProt ID O43521
• Background: Bim Monoclonal Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
• Synonyms: BAM; BIM; BOD

Reference Data

• Protein Families: Druggable Genome