BATF Rabbit Polyclonal Antibody

CAT#: TA319824

Rabbit Polyclonal BATF Antibody

Product Images

Western blot analysis of BATF in rat spleen tissue lysate with BATF antibody at 1 ?g/ml

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  Immunofluorescence of BATF in human spleen tissue with BATF antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 0.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: BATF antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BATF.
• Formulation: BATF Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: BATF Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 14 kDa
• Gene Name: basic leucine zipper ATF-like transcription factor
• Database Link:
  NP_006390
  Entrez Gene 53314 MouseEntrez Gene 299206 RatEntrez Gene 10538 Human
  UniProt ID Q16520
• Background: BATF Antibody: BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
• Synonyms: B-ATF; BATF1; SFA-2; SFA2

Reference Data

• Protein Families: Transcription Factors