SIRT5 Chicken Polyclonal Antibody

CAT#: TA319855

Chicken Polyclonal SIRT5 Antibody

Product Images

Western blot analysis of SIRT5 in human liver tissue lysate with SIRT5 antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse
• Host: Chicken
• Isotype: IgY
• Clonality: Polyclonal
• Immunogen: SIRT5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SIRT5.
• Formulation: SIRT5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SIRT5 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: sirtuin 5
• Database Link:
  NP_001180196
  Entrez Gene 68346 MouseEntrez Gene 23408 Human
  UniProt ID Q9NXA8
• Background: SIRT5 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.
• Synonyms: SIR2L5

Reference Data

• Protein Families: Druggable Genome, Transcription Factors