BANP Rabbit Polyclonal Antibody
Other products for "BANP"
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | WB: 1 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | BANP antibody was raised against a 14 amino acid synthetic peptide near the center of human BANP. |
Formulation | BANP Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | BANP Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | BTG3 associated nuclear protein |
Database Link | |
Background | BANP Antibody: BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen. BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest. p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop. BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling. Furthermore, BANP can modulate NF-κB transactivation and can inhibit tumorigenesis by regulating NF-κB target genes. Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix. |
Synonyms | BEND1; SMAR1; SMARBP1 |
Reference Data |
Documents
Product Manuals |
FAQs |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.