Protor 1 (PRR5) Rabbit Polyclonal Antibody

CAT#: TA319960

Rabbit Polyclonal PRR5 Antibody

Product Images

Western blot analysis of PRR5 in SK-N-SH cell lysate with PRR5 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide

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  Immunohistochemistry of PPR5 in mouse brain tissue with PPR5 antibody at 5 ug/mL.

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  Immunofluorescence of PPR5 in mouse brain tissue with PPR5 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PRR5 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human PRR5.
• Formulation: PRR5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: PRR5 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: proline rich 5
• Database Link:
  NP_001017528
  Entrez Gene 109270 MouseEntrez Gene 315189 RatEntrez Gene 55615 Human
  UniProt ID P85299
• Background: PRR5 Antibody: Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-beta expression.
• Synonyms: FLJ20185k; PP610; PROTOR-1; PROTOR1