SYNPO2L Rabbit Polyclonal Antibody

CAT#: TA320023

Rabbit Polyclonal SYNPO2L Antibody

Product Images

Western blot analysis of SYNPO2L in human thymus tissue lysate with SYNPO2L antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 5 ug/mL.

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  Immunofluorescence of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SYNPO2L antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SYNPO2L.
• Formulation: SYNPO2L Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SYNPO2L Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: synaptopodin 2 like
• Database Link:
  NP_001107605
  Entrez Gene 68760 MouseEntrez Gene 79933 Human
  UniProt ID Q9H987
• Background: SYNPO2L Antibody: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
• Synonyms: FLJ12921