YPEL3 Rabbit Polyclonal Antibody

CAT#: TA320038

Rabbit Polyclonal YPEL3 Antibody

Product Images

Western blot analysis of YPEL3 in A-20 cell lysate with YPEL3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide

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  Immunofluorescence of YPEL3 in A20 cells with YPEL3 antibody at 5 ug/mL.

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  Immunocytochemistry of YPEL3 in A20 cells with YPEL3 antibody at 2.5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: YPEL3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human YPEL3.
• Formulation: YPEL3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: YPEL3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: yippee like 3
• Database Link:
  NP_113665
  Entrez Gene 66090 MouseEntrez Gene 293491 RatEntrez Gene 83719 Human
  UniProt ID P61236
• Background: YPEL3 Antibody: YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
• Synonyms: MGC10500