TET3 Rabbit Polyclonal Antibody

CAT#: TA320140

Rabbit Polyclonal TET3 Antibody

Product Images

Western blot analysis of TET3 in SK-N-SH cell lysate with TET3 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunofluorescence of TET3 in human brain tissue with TET3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TET3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TET3.
• Formulation: TET3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: Lot Dependent
• Purification: TET3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 183 kDa
• Gene Name: tet methylcytosine dioxygenase 3
• Database Link:
  NP_659430
  Entrez Gene 194388 MouseEntrez Gene 680576 RatEntrez Gene 200424 Human
  UniProt ID O43151
• Background: TET3 Antibody: TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.
• Synonyms: hCG_40738

Reference Data

• Protein Families: Transcription Factors