CREB1 Goat Polyclonal Antibody

CAT#: TA320216

Goat Polyclonal CREB1 (aa96-109) Antibody

Product Images

TA320216 (0.1ug/ml) staining of Jurkat (A) and NIH3T3 (B) nuclear lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.1-0.3ug/ml, ELISA: 1:128,000
• Reactivities: Human, Mouse
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-DSQESVDSVTDSQK, from the internal region of the protein sequence according to NP_004370.1; NP_604391.1
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36.7 kDa
• Gene Name: cAMP responsive element binding protein 1
• Database Link:
  NP_004370
  Entrez Gene 12912 MouseEntrez Gene 607922 DogEntrez Gene 1385 Human
  UniProt ID P16220
• Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
• Synonyms: CREB

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Antigen processing and presentation, Huntington's disease, Melanogenesis, Prostate cancer