Cd274 Rat Monoclonal Antibody [Clone ID: 1-111A]

CAT#: TA320254

Rat Anti-Mouse PD-L1 / CD274 Purified (50 ug)

Product Images

Staining of C57Bl/6 splenocytes with 0.25 ug Rat IgG2a K Isotype Control Purified (open histogram) or 0.25 ug Anti-Mouse CD274 (B7-H1) Purified (filled histogram) followed by Anti-Rat IgG Biotin and Streptavidin PE. Total viable cells were used for analysis.

Specifications

Product Data

• Clone Name: 1-111A
• Applications: FC
• Recommended Dilution: Flow
• Reactivities: Mouse
• Host: Rat
• Clonality: Monoclonal
• Formulation: Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD274 antigen
• Database Link:
  NP_068693
  Entrez Gene 60533 Mouse
  UniProt ID Q9EP73
• Background: The 1-111A monoclonal antibody reacts with mouse B7-H1, also known as PD-L1. B7-H1, a member of the B7 family, has a predicted molecular weight of approximately 40 kDa and belongs to the Ig superfamily. B7-H1 is expressed on a majority of leukocytes including T, B, NK and DC. B7-H1 is a ligand for PD-1. Interaction of PD-1 with either PD-L1 (B7-H1) or PD-L2 (B7-DC) results in inhibition of T and B cell responses. Preliminary testing suggests that 1-111A and MIH5 (Cat. No. 14-5982) cross-block each other.
• Synonyms: B7-H; B7-H1; B7H1; MGC142294; MGC142296; PD-L1; PDCD1L1; PDCD1LG1; PDL1